Monthly Archives: March 2011

What exactly is a quadrupole MS anyway?

Many mass spectrometers (like our Shimadzu 5050A) operate by shooting an electron stream at a sample causing the molecules to fragment.  The ions formed have a +1 charge because of the electron lost by the broken bond.  Masses of interest … Continue reading

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How To Get Rid Of Air In An HPLC

Air is kryptonite to an HPLC pump.  Although, it is a common problem when you’re delivering liquids at such high pressures.  Air can easliy get in the lines and into your column if you’re not careful.  At that point you … Continue reading

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